Figure 6. The effect of 1α,25(OH)₂D₃ on mRNA expression in T cells from SLE patients.

(A) The effect of 1α,25(OH)₂D₃ on VDR mRNA expression in T cells from SLE patients. (B) The effect of 1α,25(OH)₂D₃ on CYP24A1 mRNA expression in T cells from SLE patients. (C) The effect of 1α,25(OH)₂D₃ on CYP27B1 mRNA expression in T cells from SLE patients. T cells were plated as described in methods and treated with 10 nM and 100 nM1α,25(OH)₂D₃ for 3h, 24h and 48h. The error bars represents the standard deviation (SD). n=16 for each experiment. * p<0.05 vs con; # p<0.05 100 nM vs 10 nM treatment.