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. 2017 Jul 8;8(37):62120–62130. doi: 10.18632/oncotarget.19097

Figure 7. The effect of Notch-1 downregulation on cell invasion.

Figure 7

(A) Left panel: Invasion assay was performed in CNE1 and CNE2 cells after Notch-1 siRNA transfection and rottlerin treatment. Right panel: Quantitative results are illustrated for left panel. CNE1: 1μM rottlerin; CNE2: 2μM rottlerin. Control: siRNA control; siRNA: Notch-1 siRNA; Both: Notch-1 siRNA + rottlerin. *P < 0.05, **P < 0.01, compared with control; #P < 0.05, compared with rottlerin treatment alone or Notch-1 siRNA transfection alone. (B-C) Top panel, the expression of Notch-1 was detected by western blotting in nasopharyngeal carcinoma with Notch-1 siRNA transfection and rottlerin treatment. Bottom panel: Quantitative results are illustrated for left panel. *P < 0.05, **P < 0.01, compared with control; #P < 0.05, compared with rottlerin treatment alone or Notch-1 siRNA transfection alone.