Table 1. CENP-I overexpression is a strong independent prognostic marker for ER+ breast cancer.

Type	No. of patients	HR (95% CI)	Prognostic strength		Adjuvant!a		Nottingham indexa
			p Value	p Value summary	p Value	p value summary	p Value	p Value summary
All	3826	1.26 (1.17-1.35)	6.13×10-10	****	0.0239	*	0.0421	*
ER+	2757	1.34 (1.22-1.47)	1.74×10-9	****	0.0313	*	0.0375	*
ER-	1039	1.02 (0.90-1.16)	0.7724	n/s	0.6375	n/s	0.6224	n/s

^a Calculated as described in [21] and [22], respectively.