Table 3. Receiver operating characteristic curve analyses showing the utility of alone or combined markers for differentiating of controls and gastric cancer.
Marker | Sensitivity | Specificity | PPV | NPV | AUC |
---|---|---|---|---|---|
CEA (ng/ml) | 0.773 | 0.876 | 0.867 | 0.786 | 0.827 (0.785-0.863) |
MPV (fL) | 0.722 | 0.827 | 0.814 | 0.739 | 0.809 (0.766-0.848) |
PDW (%) | 0.717 | 0.849 | 0.832 | 0.741 | 0.863 (0.824-0.896) |
CEA+MPV | 0.820 | 0.838 | 0.841 | 0.816 | 0.889 (0.854-0.919) |
CEA+PDW | 0.835 | 0.908 | 0.905 | 0.840 | 0.939 (0.910-0.961) |
Abbreviations: PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve; CEA, carcinoembryonic antigen; MPV, mean platelet volume; PDW, platelet distribution width.