Table 4. Receiver operating characteristic curve analyses showing the utility of alone or combined markers for differentiating of gastric ulcer and gastric cancer.
Marker | Sensitivity | Specificity | PPV | NPV | AUC |
---|---|---|---|---|---|
CEA (ng/ml) | 0.655 | 0.712 | 0.698 | 0.670 | 0.692 (0.643-0.737) |
MPV (fL) | 0.856 | 0.754 | 0.779 | 0.837 | 0.853 (0.813-0.887) |
PDW (%) | 0.985 | 0.974 | 0.974 | 0.984 | 0.990 (0.975-0.998) |
CEA+MPV | 0.851 | 0.770 | 0.789 | 0.835 | 0.876 (0.839-0.907) |
CEA+PDW | 0.990 | 0.979 | 0.980 | 0.989 | 0.996 (0.984-1.000) |
Abbreviations: PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve; CEA, carcinoembryonic antigen; MPV, mean platelet volume; PDW, platelet distribution width.