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Adenocarcinoma histology (P = 0.001), increased CA19-9 (P = 0.003), patients belonging to poor risk group in Culine’s model (P < 0.001), CK20 positivity (P = 0.002), metastasis not confined to the lymph nodes (P = 0.0015), and presence of bone metastasis (P = 0.017) were factors related with unfavorable clinical outcome.
