Table 3. Multivariable analysis of clinicopathologic factors related to survival.
| Variable | HR | 95% CI | P |
|---|---|---|---|
| Culine’s prognostic model | |||
| Poor risk group vs. good risk group | 3.88 | 1.75-8.64 | 0.001 |
| Histologic subtype | |||
| Adenocarcinoma vs. other subtypes | 1.51 | 0.76-2.97 | 0.24 |
| Lymph node metastasis | |||
| Lymph node involement only vs. lymph node and distant organ metastasis | 0.86 | 0.34-2.16 | 0.76 |
| Bone metastsis | |||
| Present vs. absent | 1.43 | 0.67-3.04 | 0.36 |
| CA19-9 level | |||
| Elevation vs. normal range | 1.98 | 0.99-3.97 | 0.053 |
| CK20 expression | |||
| Positivity vs. negativity | 3.31 | 1.42-7.70 | 0.005 |