Table 1. Characteristics of AML patients based on marital status (n=50825) a.
Characteristic | All patients no. (%) | Marital status | |||||
---|---|---|---|---|---|---|---|
Married no. (%) | Widowed no. (%) | Never married no. (%) | Divorced no. (%) | Separated no. (%) | P-value b | ||
No. of patients | 50825(100) | 30006(100) | 8515(100) | 7927(100) | 3936(100) | 441(100) | - |
Sex Male Female |
27510(54.1) 23315(45.9) |
18990(63.3) 11016(36.7) |
2238(26.3) 6267(73.7) |
4248(53.6) 3679(46.4) |
1809(46.0) 2127(54.0) |
215(48.8) 226(51.2) |
<0.001 |
Age 16-35 36-55 56-75 76-95 >95 |
4540(8.9) 9399(18.5) 20516(40.4) 16176(31.8) 194(0.4) |
1529(5.1) 6182(20.6) 13915(46.4) 8354(27.8) 26(0.1) |
10(0.1) 153(1.8) 2303(27.0) 5903(69.3) 146(1.8) |
2812(35.5) 1916(24.2) 2131(26.9) 1047(13.2) 21(0.2) |
137(3.5) 1010(25.7) 1995(50.7) 793(20.1) 1(0.0) |
52(11.8) 138(31.3) 172(39.0) 79(17.9) 0(0.0) |
<0.001 |
Race Black White Other (American Indian/AK Native, Asian/Pacific Islander) Unknown |
4102(8.1) 42610(83.8) 4013(7.9) 100(0.2) |
1646(5.5) 25746(85.8) 2567(8.6) 47(0.1) |
655(7.7) 7323(86.0) 528(6.2) 9(0.1) |
1261(15.9) 5927(74.8) 703(8.9) 36(0.4) |
466(11.8) 3281(83.4) 182(4.6) 7(0.2) |
74(16.8) 333(75.5) 33(7.5) 1(0.2) |
<0.001 |
AML subtype AML, NOS Acute promyelocytic leukemia Acute myelomonocytic leukemia AML with RPN1/EVI1 fusion gene AML with CBFB/MYH11 fusion gene AML with RUNX1/RUNX1T1 fusion gene AML with MLLT3/MLL fusion gene AML with RBM15/MKL1 fusion gene AML with DEK/NUP214 fusion gene AML with minimal differentiation AML without maturation AML with maturation AML with myelodysplasia-related changes Acute erythroid leukemia Acute megakaryoblastic leukemia Therapy-related myeloid neoplasm |
30005(59.0) 3833(7.5) 4942(9.7) 22(0.0) 503(1.0) 619(1.2) 280(0.6) 21(0.0) 28(0.0) 1203(2.4) 1922(3.8) 2243(4.4) 3132(6.2) 864(1.7) 312(0.6) 896(1.9) |
17442(58.1) 2284(7.6) 2958(9.9) 13(0.0) 283(0.9) 353(1.2) 141(0.5) 14(0.0) 15(0.0) 703(2.3) 1161(3.9) 1325(4.4) 2009(6.9) 546(1.8) 190(0.6) 569(1.9) |
5702(67.0) 287(3.4) 801(9.4) 4(0.0) 30(0.4) 54(0.6) 44(0.5) 2(0.0) 3(0.0) 224(2.6) 274(3.2) 322(3.8) 515(6.0) 122(1.4) 38(0.4) 95(1.3) |
4317(54.5) 951(12.0) 757(9.5) 3(0.0) 126(1.6) 142(1.8) 65(0.8) 3(0.0) 10(0.0) 182(2.3) 329(4.2) 373(4.7) 356(4.5) 112(1.4) 59(0.7) 142(2.0) |
2301(58.5) 271(6.9) 378(9.6) 0(0) 56(1.4) 61(1.5) 27(0.7) 2(0.0) 0(0.0) 87(2.2) 146(3.7) 196(5.0) 228(5.8) 78(2.0) 22(0.6) 79(2.1) |
243(55.1) 40(9.1) 48(10.9) 2(0.6) 8(1.8) 9(1.8) 3(0.7) 0(0.0) 0(0.0) 7(1.6) 12(2.7) 27(6.1) 24(6.1) 6(1.4) 3(0.7) 11(2.4) |
<0.001 |
Adjuvant therapy None Beam radiation or radioisotopes Unknown |
48683(95.8) 1896(3.7) 246(0.5) |
2867(95.6) 1201(4.0) 134(0.4) |
8390(98.5) 64(0.8) 61(0.7) |
7430(93.7) 467(5.9) 30(0.4) |
3772(95.8) 146(3.7) 18(0.5) |
420(95.2) 18(4.1) 3(0.7) |
<0.001 |
Cause of Death Alive or dead of other cause Dead (attributable to AML) Not first tumor |
11317(22.3) 27406(53.9) 12102(23.8) |
6653(22.2) 15891(53.0) 7462(24.8) |
895(10.5) 5285(62.1) 2335(27.4) |
2819(35.6) 3829(48.3) 1279(16.1) |
829(21.1) 2170(55.1) 937(23.8) |
121(27.4) 231(52.4) 89(20.2) |
<0.001 |
Abbreviation: NOS, no other specific; SEER, Surveillance, Epidemiology and End Results; AML, acute myeloid leukemia.
aData represented number of patients.
bP value of the Chi-square test or Wilcoxon-Mann-Whitney test refers to comparison for the differences in proportions among subgroups.