Table 3. Univariate and multivariate CSS analysis, based on sex, age, AML subtype and adjuvant therapy, of AML patients with different marital status.
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| Sex Male Married Widowed Never married Divorced Separated Female Married Widowed Never married Divorced Separated |
Reference 1.623 (1.533-1.719) 0.763 (0.729-0.800) 1.098 (1.031-1.170) 0.976 (0.814-1.170) Reference 2.115 (2.029-2.205) 0.846 (0.801-0.894) 1.131 (1.061-1.207) 0.976 (0.810-1.176) |
<0.001 <0.001 0.004 0.790 <0.001 <0.001 <0.001 0.797 |
Reference 1.197 (1.129-1.296) 1.157 (1.101-1.215) 1.179 (1.106-1.256) 1.164 (0.971-1.396) Reference 1.318 (1.260-1.379) 1.165 (1.102-1.232) 1.121 (1.051-1.195) 1.131 (0.939-1.363) |
<0.001 <0.001 <0.001 0.101 <0.001 <0.001 0.001 0.196 |
| Age (years) 16-55 Married Widowed Never married Divorced Separated >55 Married Widowed Never married Divorced Separated |
Reference 1.320 (1.066-1.635) 0.981 (0.928-1.037) 1.273 (1.166-1.390) 1.116 (0.903-1.380) Reference 1.505 (1.457-1.555) 1.111 (1.058-1.167) 1.043 (0.990-1.099) 1.071 (0.098-1.262) |
0.011 0.501 <0.001 0.308 <0.001 <0.001 0.115 0.417 |
Reference 1.320 (1.065-1.636) 1.146 (1.079-1.218) 1.265 (1.158-1.382) 1.176 (0.952-1.453) Reference 1.279 (1.233-1.326) 1.139 (1.085-1.197) 1.116 (1.059-1.176) 1.123 (0.952-1.324) |
0.011 <0.001 <0.001 0.134 <0.001 <0.001 <0.001 0.169 |
| AML subtype AML, NOS Married Widowed Never married Divorced Separated Others Married Widowed Never married Divorced Separated |
Reference 1.745 (1.679-1.813) 0.811 (0.775-0.849) 1.078 (1.019-1.141) 1.038 (0.881-1.223) Reference 1.827 (1.728-1.932) 0.771 (0.728-0.816) 1.064 (0.989-1.146) 0.852 (0.689-1.054) |
<0.001 <0.001 0.009 0.654 <0.001 <0.001 0.098 0.141 |
Reference 1.321 (1.267-1.377) 1.157 (1.104-1.213) 1.154 (1.090-1.222) 1.255 (1.065-1.478) Reference 1.292 (1.216-1.372) 1.180 (1.112-1.253) 1.135 (1.054-1.222) 1.040 (0.840-1.287) |
<0.001 <0.001 <0.001 0.007 <0.001 <0.001 0.001 0.719 |
| Adjuvant therapy None Married Widowed Never married Divorced Separated Beam radiation or radioisotopes Married Widowed Never married Divorced Separated |
Reference 1.763 (1.708-1.820) 0.788 (0.760-0.817) 1.066 (1.019-1.116) 0.929 (0.813-1.061) Reference 3.049 (2.430-3.827) 0.874 (0.748-1.020) 1.170 (0.928-1.475) 1.289 (0.728-2.283) |
<0.001 <0.001 0.006 0.276 <0.001 0.088 0.185 0.384 |
Reference 1.299 (1.255-1.345) 1.157 (1.114-1.201) 1.148 (1.097-1.203) 1.119 (0.979-1.278) Reference 1.483 (1.148-1.916) 1.252 (1.052-1.489) 1.134 (0.898-1.430) 1.865 (1.049-3.318) |
<0.001 <0.001 <0.001 0.100 0.003 0.011 0.291 0.034 |
Abbreviation: CSS, cancer-specific death; HR, hazard ratio; CI, confidence interval; AML, acute myeloid leukemia; NOS, no other specific;