Table 3. Main results of the pooled analysis.
Survival | Variables | No. of studies | Rondom-effects model or fixed-effects model | Heterogeneity | |||
---|---|---|---|---|---|---|---|
No. of patients | Pooled HR | 95%CI | I2 | P | |||
OS | All | 19 | 2009 | 0.59 | 0.39-0.90 | 85.20% | 0.000 |
Type | |||||||
genital system tumors | 4 | 301 | 0.42 | 0.27-0.66 | 0.00% | 0.431 | |
digestive system | 6 | 723 | 0.65 | 0.29-1.47 | 80.40% | 0.000 | |
respiratory system | 3 | 250 | 0.60 | 0.23-1.62 | 92.60% | 0.000 | |
urinary system | 3 | 314 | 0.54 | 0.04-4.74 | 93.90% | 0.000 | |
others | 3 | 421 | 0.74 | 0.23-2.37 | 80.9% | 0.005 | |
Sample | |||||||
>100 | 10 | 1325 | 0.44 | 0.30-0.64 | 67.70% | 0.001 | |
<100 | 9 | 684 | 0.83 | 0.41-1.70 | 84.40% | 0.000 | |
Country | |||||||
China | 16 | 1752 | 0.55 | 0.35-0.86 | 85.80% | 0.000 | |
Other countries | 3 | 257 | 0.98 | 0.19-5.10 | 87.20% | 0.000 | |
Method | |||||||
Univariate | 10 | 1069 | 0.56 | 0.38-0.82 | 52.40% | 0.032 | |
Multivariate | 9 | 940 | 0.57 | 0.28-1.17 | 89.80% | 0.000 |