Table 1. Chromosomal aberrations in MDS.
| Aberration type | Position | Significance | Reference |
|---|---|---|---|
| del(5q) | 5q31 | AML evolution | 21 |
| trisomy 8 | cT8M | intermediate-risk | 38,39 |
| del(20q) | 20q11.2- q13.1 | exacerbate malignancy | 46,47 |
| del (7q) | 7q22, 7q34 | contribute to hematopoietic aberration | 56 |
| monosomy 7 | -7 | higher-risk, poor prognosis | 66–68 |
| complex karyotype | multiple | unfavorable outcome | 76 |