Table 1. Chromosomal aberrations in MDS.
Aberration type | Position | Significance | Reference |
---|---|---|---|
del(5q) | 5q31 | AML evolution | 21 |
trisomy 8 | cT8M | intermediate-risk | 38,39 |
del(20q) | 20q11.2- q13.1 | exacerbate malignancy | 46,47 |
del (7q) | 7q22, 7q34 | contribute to hematopoietic aberration | 56 |
monosomy 7 | -7 | higher-risk, poor prognosis | 66–68 |
complex karyotype | multiple | unfavorable outcome | 76 |