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. 2017 May 9;8(37):62716–62729. doi: 10.18632/oncotarget.17698

Table 1. Chromosomal aberrations in MDS.

Aberration type Position Significance Reference
del(5q) 5q31 AML evolution 21
trisomy 8 cT8M intermediate-risk 38,39
del(20q) 20q11.2- q13.1 exacerbate malignancy 46,47
del (7q) 7q22, 7q34 contribute to hematopoietic aberration 56
monosomy 7 -7 higher-risk, poor prognosis 66–68
complex karyotype multiple unfavorable outcome 76