| MC |
visible chromosomal aberrations |
Simple, whole chromosomal view |
Low resolution, Can’t detect UPD |
800 rmb |
| FISH |
small and hidden chromosomal aberrations |
Not rely on proliferating cells, High sensitivity |
only detect particular chromosomal aberrations |
2000 rmb |
| SKY |
Unknown and complex chromosomal aberrations |
display better pictures of karyotypes |
Can’t detect structural aberration, low resolution |
3500 rmb |
| SNP-A |
Cryptic and complex chromosomal aberrations |
high-resolution, can detect UPD |
Can’t detect balanced translocation and inversion |
5000 rmb |
| Array-CGH |
Detect CNV and UPD |
genome-wide analysis high-resolution |
Can’t detect balanced rearrangements, low-level mosaicism and polyploidy |
4500 rmb |
| Sequencing |
CNV and structural variants, unknown mutation or aberrations |
genome-wide analysis improved sensitivity monitor clonal mutations |
Expensive, time-consuming, complicated bioinformatic analysis |
6000 rmb |