Figure 2. Network of Included Studies With Available Direct Comparisons for Primary Efficacy Outcome (≥5%Weight Loss).

The size of the nodes and the thickness of the edges are weighted according to the number of studies evaluating each treatment and direct comparison, respectively. The study by Swinburn et al³⁷ reported only continuous weight loss outcomes and is not included in this network. Network of included studies for all other outcomes is shown in eFigure 1 in the Supplement.