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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Addict Biol. 2017 Mar 28;23(1):219–229. doi: 10.1111/adb.12504

Figure 1.

Figure 1

A. Map of coronal sections through the PFC showing all cannula placements for experiments 2, 4, and 5. The circled regions correspond to areas where tissue punches were taken for experiments 1 and 3 (AP ~+4.68mm–+2.76mm relative to bregma). B. Schematic of the experimental timelines for all experiments. Final sample sizes: Experiment 1-(0 μM: n=5, 0.5 μM: n=7, 1 μM: n=6, 5 μM: n=7); Experiment 2- (TC-2153 (1μM): n=9, vehicle: n=13); Experiment 3- (Saline+Vehicle: n=10, Saline+TC- 2153: n=7, Cocaine+Vehicle: n=8, Cocaine+TC-2153: n=9); Experiment 4- (TC-2153 (1 μM): n=7, Vehicle: n=4); Experiment 5- (TC-2153 (5 mg/kg): n=10, Vehicle: n=11).