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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Addict Biol. 2017 Mar 28;23(1):219–229. doi: 10.1111/adb.12504

Figure 2.

Figure 2

A single intra-PrL microinfusion of TC-2153 (1 μM) increased p-ERK in naïve rats. Rats were infused with vehicle (0) or 0.5, 1, or 5 μM of TC-2153 and rapidly decapitated two hours later to determine the optimal concentration of TC-2153 that increased p-ERK when microinfused into the PrL cortex. A. Only 1 μM TC-2153 increased p-ERK relative to vehicle-infused rats (*p<0.05). B. There was no difference in t-ERK/calnexin. Representative chemiluminescent peaks for p-ERK (C) and t-ERK multiplexed with calnexin (D) for groups in experiment 1.