Table 1.
Baseline characteristics of study cohort.
| Characteristic | Total cohort (n = 49) |
|---|---|
| Age, mean (SD) | 10.3 (3.6) |
| Male sex, N (%) | 31 (63) |
| Homozygous dF508, N (%) | 36 (74) |
| PEx in 2 years before inclusion, N (%) | 23 (47) |
| Pseudomonas aeruginosa at inclusion*, N (%) | 15(31) |
| ABPA at inclusion*, N (%) | 2 (4) |
| BMI, median (IQR) | 16.8 (16.0–18.1) |
| BMI-SDS, mean (SD) | 0.14 (0.8) |
| FEV1% predicted value, mean (SD) | 87.4 (18.1) |
| FVC % predicted value, mean (SD) | 92.4 (16.4) |
| FEV1/FVC, mean (SD) | 0.8 (0.1) |
| RV % predicted value, mean (SD)# | 130.9 (42.7) |
| TLC % predicted value, mean (SD)# | 101.1 (12.0) |
| Prophylactic antibiotics, N (%) | 28 (57) |
| Inhalation corticosteroids, N (%) | 16 (33) |
*Treated because of positive sputum culture. #Total n = 37 (12 children did not perform static lung function). Abbreviations: ABPA, Allergic Bronchopulmonary Aspergillosis; BMI, body mass index; FEV1, Forced Expiratory Volume in 1 second; FVC, Forced Vital Capacity; PEx, pulmonary exacerbation; RV, Residual Volume; SD, Standard deviation; TLC, Total Lung Capacity. All p > 0.05.