Table 1.
The time course of alpha-fetoprotein, beta-human chorionic gonadotropin, and lactate dehydrogenase levels.
| Date | Events | B-HCG (mIU/mL) | LDH (U/L) | AFP (IU/mL) |
|---|---|---|---|---|
| Dec 2014 | Initial presentation | 462,748 | 1108 | <1 |
| Jan 2015 | Received stereotactic radiation to the brain metastases. Initiation of VIP | 480 | 205 | 1 |
| Mar 2015 | Completed 4 cycles of VIP chemotherapy | 295 | 213 | 1 |
| Mar-June 2015 | Left radical orchiectomy and RPLND | 5 | 188 | <1 |
| Jul 2015 | One month after surgery | 125 | 131 | <1 |
| Sep-Nov 2015 | High dose carboplatin/etoposide and autologous PBSCT | 4143 | 350 | <1 |
| Dec 2015 | One month after completion of PBSCT | 85 | 207 | 1 |
| Jan 2016 | Initiation of gemcitabine/oxaliplatin | 624 | 223 | 1 |
| Jan 2016 | Admitted to hospital due to intractable nausea, vomiting and fever | 11,519 | 207 | 3 |
| Mar 2016 | Initiation of pembrolizumab | 14,677 | - | - |
| Mar 2016 | Three weeks after first cycle of pembrolizumab | 45,397 | 1249 | 1 |
| Apr 2016 | Initiation of paclitaxel | 98,648 | - | - |
VIP, cisplatin, etoposide, and ifosfamide; RPLND, retroperitoneal lymph node dissection; PBSCT, peripheral blood hematopoietic stem cell transplant; HCG, human chorionic gonadotropin; LDH, lactate dehydrogenase; AFP, alpha-fetoprotein.