Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Sep 26;5(18):e13441. doi: 10.14814/phy2.13441

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

MiR‐339 expression was decreased in pulmonary arteries of MCT‐induced PAH rats. (A) Histogram showed the miR‐339 expression in various organs in rats, ▵Ct = Ct(miR‐339)‐Ct(sno202), n = 5. (B) The ratio of right ventricle (RV) and left ventricle (LV) plus ventricular septum (S) RV/(LV+S) in MCT‐induced rats was elevated significantly (n = 4) compared with that in the controls (n = 4). (C) Right ventricular systolic pressure (RVSP) in MCT‐induced rats was elevated significantly (n = 4) compared with that in the controls (n = 4). (D) Expression of PDGFR β mRNA in pulmonary arteries of MCT‐induced rats was increased significantly (n = 4) compared with that in the controls (n = 4). (E) Expression of miR‐339 in pulmonary arteries of MCT‐induced rats was decreased significantly (n = 4) compared with that in the controls (n = 4). MCT represented MCT‐treated rats, NS represented normal saline‐treated rats; different significance was assessed with Student's t test, *P < 0.01.