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. 2017 Jul 3;6(3):19. doi: 10.3390/cells6030019

Table 1.

Mechanical properties, measured in terms of compliance and burst pressure, and structural properties, measured in terms of wall thickness, inner diameter, and vessel wall thickness-to-radius (T:R) ratio, from a selection of studies concerning native tissue, synthetic grafts, in vitro tissue-engineered grafts, and in situ tissue-engineered grafts. Compliance is measured in the physiological range, i.e., 80–120 mmHg, unless indicated otherwise.

Artery Material Design Model Compliance
(%/100 mmHg)
Burst
Pressure (mmHg)
Thickness (μm) Inner
Diameter (mm)
T:R (-) Ref.
Native AA n.a. rat 6.7 3415 150 1 0.3 [13]
CA n.a. porcine 18.7 * 3320 614 n.d. n.d. [14]
IMA n.a. porcine 11.2 2100 231 n.d. n.d. [15]
FA n.a. sheep 3.3 2297 770 n.d. n.d. [16]
FA n.a. sheep 8.52 n.d. n.d. n.d. n.d. [17]
CA n.a. sheep 11.98 10,950 750 2.25 0.67 [18]
FA n.a. human 2.6 n.d. n.d. n.d. n.d. [19]
IMA n.a. human 4.5–6.2 2031–4225 350–710 n.d. n.d. [9]
IMA n.a. human 11.5 3196 300–800 1.5–4.5 0.35–0.40 [20]
Synthetic PGA or PLLA + PLCL non-woven porous graft n.a. n.d. 2710–2790 150–250 0.7–0.9 0.33–0.71 [21]
PCL e-spun microfibrous graft n.a. 0.58–0.92 850–1800 415 6 0.14 [22]
PLLA e-spun microfibrous graft n.a. 0.93 n.d. 390 4.9 0.16 [17]
PLLA/PLCL bi-layered graft with inner e-spun and outer weft-knitted layer n.a. 1.8 21,750 330 3.2 0.21 [23]
PLLA/PHD bi-layered graft with different blend rations n.a. 1.12 1775 230 5 0.09 [24]
PEUU bi-layered graft with large inner pores and dense outer pores n.a. 4.6 2300 743 4.7 0.32 [15]
poly(diol citrate) non-woven porous graft n.a. 12.7 250 160 3.65 0.09 [25]
In vitro PGA non-woven porous graft 10 weeks under pulsatile conditions n.d. 1300–1337 442 3 0.29 [26]
PGA non-woven porous graft 1 week static, 4 weeks dynamic strain (1%) n.d. 906 1000 3 0.67 [27]
human fibroblast sheets sheet-based 8 weeks static, 10 weeks maturation 1.5 3468 407 4.2 0.19 [9]
fibrin fibroblast-seeded fibrin gel 2 weeks static, 5–7 weeks dynamic strain (7%) 2.4–4.4 1366–1542 280–430 2–4 0.22–0.28 [16]
PGA non-woven porous graft 7–10 weeks dynamic strain (2.5%) 3.3 3337 1000 6 0.33 [8]
PGA non-woven porous graft 7–8 weeks dynamic strain (1.5%) 3.5 * 800 220 3 0.15 [14]
human fibroblast sheets sheet-based 6–8 weeks static, 12 weeks maturation 3.54 3490 200–600 2.4–6.6 0.18 [20]
In situ PCL/CS e-spun nanofibrous graft sheep (CA), 6 months 6.58 10,275 1180 2.9 0.81 [18]
PEOT/BPT/PCL PEOT/BPT solid rod with external e-spun PCL sheet porcine (SC), 4 weeks 7.46 3947 700 2 0.70 [10]
PCL e-spun nano/microfibrous graft rat (AA), 1.5–18 months 7.8 3280 650 2 0.65 [28]
PGS/PCL porous PGS reinforced with PCL sheet rat (AA), 3 months 11 2360 290 0.72 0.81 [13]

AA, abdominal artery; CA, carotid artery; FA, femoral artery; IMA, internal mammary artery; PGA, polyglycolic acid; PLLA,poly-L-lactic acid; PLCL, 50:50 copolymer solution of L-lactide and ε-caprolactone; PCL, poly(caprolactone); PEUU, poly(esterure-thane)urea; CS, chitosan; PEOT/BPT, poly(ethylene oxide terephthalate)-poly(butylene terephthalate; SC, subcutaneous; PGS, poly(glycerol sebacate); n.a., not applicable; n.d., not determined; *, 80–200 mmHg; , 60–190 mmHg.