Table 2.

Scoring anchors for the Transdiagnostic CGI-S and CGI-Improvement (CGI-I).

T-CGI-Severity		T-CGI-Improvement
Severity Rating	Severity Level Description	Improvement Rating	Improvement Level Description
1. Normal	Symptoms are rarely present and occur only in contextually appropriate circumstances. The patient reports functioning at or very close to their full capacity.	1. Very much improved	Both the patient and the clinician agree that he/she has improved greatly from baseline, both in terms of symptoms and role functioning. The T-CGI-S score should be no more than mild (3), but in rare cases may be moderate (4) if the baseline severity was very high (7). If the T-CGI-S score is Normal (1), then the T-CGI-I score should be 1.
2. Borderline ill	Symptoms are few in number and only intermittently present, and usually no more than mild severity. There is little or no interference in role functioning.	2. Much improved	The patient has experienced clear and clinically meaningful reductions in symptoms, along with some improvement in role functioning, but distress or impairment from the illness persists. The T-CGI-S score should be no more than moderate (4), but in rare cases may be markedly ill (5) if the baseline severity was very high (7).
3. Mildly ill	Symptoms are clearly present and cause distress, but there is only minimal or no reduction in functioning.	3. Minimally improved	There is a detectable improvement in symptoms but little or no improvement in role functioning. The clinical significance of the changes is no more than minimal.
4. Moderately ill	Symptoms are present every day or nearly every day but may diminish at times. Substantial distress is present but bearable. Functioning in important roles is somewhat reduced, or maintained only through high levels of perceived effort. Suicidal thoughts may be present, but there is usually a desire to live.	4. No change	Symptoms and role functioning have not changed in any meaningful way since the baseline.
5. Markedly ill	Symptoms are highly distressing and the patient struggles greatly to function in important life roles. Active suicidal ideation may be present.	5. Minimally worse	There is a detectable worsening in symptoms but little or no change in role functioning. The clinical significance of the changes is no more than minimal.
6. Severely ill	Symptoms are nearly constant and highly distressing, and the patient is unable to function in important life roles. Active suicidal ideation may be present.	6. Much worse	Symptoms and role functioning are clearly worse from baseline. A change in treatment should be strongly considered.
7. Among the most extremely ill patients	Symptoms are continuously present at a very severe level. The person is unable to maintain basic functioning. Active suicidal thoughts are usually present. Hospitalization is usually required.	7. Very much worse	Symptoms and role functioning are dramatically worse than baseline. A change in treatment is definitely needed.