Figure 3.

Typical phospholipids used in studies involving membrane-mediated interactions with A$\beta$ include: 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC) which is a fully saturated and good model of bilayer properties; 1,2-dimyristoyl-sn-glycero-3-phosphorylglycerol (DMPG) which allows for modification of bilayer surface charge; 1,2-dimyristoyl-sn-glycero-3-phospho-l-serine (DMPS) which is an anionic lipid for understanding electrostatic surface potential; and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) which is the standard model membrane for eukaryotic membranes due to its half-saturated, half-unsaturated organization and fluidity in bilayer systems. Monomeric forms of the A${\beta }_{1-42}$ and A${\beta }_{25-35}$ are shown from solution NMR (PDB structures 1Z0Q and 1QWP).