Table 4.

Utility estimates used to calculate quality-adjusted progression-free life years (QAPFLYs) associated with treatment.

Adverse Event	Utility Estimate	Reference
Base-line, stable disease, no toxicity	0.653	[20]
Anemia (grade 3–4)	0.583	[21]
Arthralgia (grade 3–4 )	0.589	[22]
Diarrhea (grade 3–4 )	0.606	[20]
Fatigue (grade 3–4 )	0.580	[20]
Febrile Neutropenia (grade 3–4 )	0.563	[20]
Infection (grade 3–4 )	0.423	[22]
Neuropathy (grade 3–4 )	0.620	[23]
Neutropenia (grade 3–4 )	0.563	[20]
Pneumonitis (grade 3–4 )	0.560	[24]
Rash (grade 3–4 )	0.621	[20]
Stomatitis (grade 3–4 )	0.610	[23]
Thrombocytopenia (grade 3–4 )	0.545	[22]