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Effects of HbVs and Empty vesicles on proliferation of Con A-stimulated rat splenic T cells. Spleen was excised from rat 24 h after injection of HbVs, empty vesicle (liposome), or saline. Then splenocytes were stimulated with Con A. The proliferative response of splenic T cells derived from both HbV-loaded and empty vesicle-loaded rats were significantly lower than those of controls (** p < 0.01).
