A1	BCL2A1—BCL2-related protein A1
A20	TNFAIP3 —Tumour necrosis factor α-induced protein 3
ABIN-1	A20 binding inhibitor of NF-κB
ADAP	Adhesion- and degranulation-promoting adaptor protein
ALCL	Anaplastic large-cell lymphoma
ALL	Acute lymphoblastic leukaemia
AML	Acute myeloid leukaemia
ARD	Ankyrin repeat domain
ATM	Ataxia telangiectasia mutated
BAD	Bcl-2-associated death promoter
BAFF	B-cell activating factor
BAK	BCL-2 antagonist/killer
BAX	BCL-2-associated X protein
BCL10	B-cell CLL/lymphoma 10
BCL-2	B-cell lymphoma 2
Bcl-XL	B-cell lymphoma-extra large
BCR	B-cell receptor
BH	BCL-2 homology
BID	BH3 interacting-domain death agonist
BIM	BCL-2-interacting mediator of cell death
BIR	Baculovirus IAP repeat
CAML	Calcium modulating ligand
CARD	Caspase recruitment domain
CBM	CARD11-BCL10-MALT1
CD40L	CD40 ligand
Cdc25A	Cell division cycle 25A
c-FLIP	Cellular FLICE/caspase8-like inhibitory protein
c-IAP	Cellular inhibitor of apoptosis
CLL	Chronic lymphocytic leukaemia
CYLD	Cylindromatosis lysine 63 deubiquitinase
DAMP	Damage-associated molecular patterns
DHMEQ	Dehydroxymethylepoxyquinomicin
DLBCL	Diffuse large B-cell lymphoma
DMAPT	Dimethylaminoparthenolide
DUB	Deubiquitination enzyme
Emi1-FBXO 5	F-box protein 5
EMT	Epithelial-mesenchymal transition
FBXW	F-box and WD repeat domain containing
FDA	US Food and Drug Administration
FL	Follicular lymphoma
GADD45β	Growth arrest and DNA damage inducible β
GBM	Glioblastoma multiforme
GRR	Glycine rich region
GSK3	Glycogen synthase kinase 3
HAT	Histone acetyltransferase
HDAC	Histone deacetylases
HL	Hodgkin’s lymphoma
HOIL-1L	RBCK1—RanBP-type and C3HC4-type zinc finger containing 1
HOIP	RNF31—Ring finger protein 31
IKK	IκB kinase
IL-1β	Interleukin 1 β
IL-1β	Interleukin 1β
IL-1βR	IL-1β receptor
IRAK	Interleukin-1 receptor-associated kinase
IκB	Nuclear factor of κ light polypeptide gene enhancer in B-cells inhibitor
JAK	Janus kinase
LPS	Lipopolysaccharide
LTβ	Lymphotoxin β
LUBAC	Linear ubiquitination assembly complex
MALT	Mucosa-associated lymphoid tissue
MALT1	Mucosa-associated lymphoid tissue lymphoma translocation protein 1
MAP	Mitogen activated protein
MAPKKK	Mitogen activated protein kinase kinase kinase
MAVS	Mitochondrial antiviral signalling protein
MCL	Mantle-cell lymphoma
MCL1	Myeloid cell leukaemia sequence 1
MDS	Myelodysplastic syndrome
MEKK	Mitogen activated protein kinase kinase
MM	Multiple myeloma
mTOR	Mechanistic target of rapamycin
MYD88	Myeloid differentiation primary response protein 88
NEDD8	Neural precursor cell-expressed developmentally down-regulated 8
NES	Nuclear export signal
NF-κB	Nuclear factor κ B (Nuclear Factor binding to the κ-Light-chain-enhancer B site)
NHL	Non-Hodgkin’s lymphoma
NIK	NF-κB-inducing kinase
NLR	NOD-like receptor
NLS	Nuclear localization signals
NOD	Nucleotide-binding oligomerisation domain
NSCLC	Non-Small Cell Lung Cancer
OTUD7B	OTU domain-containing protein 7B
PAMP	Pathogen-associated molecular pattern
PAR	Poly(ADP-ribose)
PARP-1	Poly(ADP-ribose)-polymerase-1
PDK	Phosphoinoisitide-dependent kinase
PDK1	3-Phosphoinositide-dependent protein kinase 1
PDLIM2	PDZ and LIM domain protein 2
PIASy	Protein inhibitor of activated STAT protein y
PIDD	p53-induced death domain protein
PKC	Protein kinase C
PP	Protein phosphatase
PTEN	Phosphatase and tensin homolog
PUMA	p53 upregulated modulator of apoptosis
RANKL	Receptor activator of NF-κB ligand
RAS	Rat sarcoma virus oncogene
RBX1	RING-box protein 1
RHD	Rel-homology Domain
RIP	Receptor interacting protein
RLH	RNA helicase
RLR	RIG-I-like receptor
SCF	SKP1-Cullin 1-F-box protein
Sharpin	SHANK-associated RH domain interacting protein
SL	Sesquiterpene lactone
SMAC	Second mitochondria-derived activator of caspases
SOCS-1	Suppressor of cytokine signalling-1
STAT	Signal transducer and activator of transcription
SUMO	Small ubiquitin-like modifiers
TAB	TAK1-associated binding protein
TACI	TNFRSF13B—TNF receptor superfamily member 13B
TAK1	Transforming growth factor β-activated kinase 1
T-ALL	T-cell acute lymphoblastic leukaemia
TBK1	TANK-binding kinase
TCR	T-cell receptor
TLR	Toll-like receptor
TME	Tumour microenvironment
TNF-R	TNF receptor
TNFSF	Tumour necrosis factor superfamily member
TNF-α	Tumour necrosis factor-α
TRADD	TNF receptor-associated death domain protein
TRAF	TNF receptor-associated factor
TRIM23	Tripartite motif protein 23
TWEAK	TNF-related weak inducer of apoptosis
UBA	Ubiquitin-activating enzyme, E1
UBC	Ubiquitin-conjugating, E2
Ubc/Uev	Ubiquitin-conjugating enzyme/ubiquitin E2 variant
UBD	Ubiquitin-binding domain
UPP	Ubiquitin-proteasome pathway
UPR	Unfolded protein response
USP	Ubiquitin-specific peptidase
WIP1	Wild-type p53-induced phosphatase 1
WM	Waldenström’s macroglobulinemia
WWOX	WW domain-containing oxidoreductase
βTrCP	β-transducin repeat-containing protein