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. 2017 Jun 22;7(3):31. doi: 10.3390/metabo7030031

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Significant metabolites identified in skeletal muscle 2 weeks after tyrosine kinase inhibitor (or vehicle control) treatment. PCA (principal components analysis) of metabolites identified in quadriceps femoris after sunitinib treatment (A). t-test significant metabolites identified in quadriceps femoris after sunitinib treatment (B). PCA (principal components analysis) of metabolites identified in quadriceps femoris after erlotinib treatment (C). t-test significant metabolites identified in quadriceps femoris after erlotinib treatment (D). N = 10/group.