Table 2.

t-test significant metabolites in sunitinib-treated tissues compared to vehicle control treated. Color-matched metabolites are highlighted if they were found in two or more tissues (blue) or in the same tissue by both drugs (red).

Sunitinib Treatment
Heart	Liver	Skeletal Muscle	Serum
Fructose Or Similar Ketohexose (↓)	Cholesterol (↑)	Adenosine/Inosine (↓)	Ethanolamine (↑)
Docosahexaenoic Acid (DHA) (↓)	Sucrose and Similar Disaccharides (↑)	Docosahexaenoic Acid (DHA) (↓)
Arachidonic Acid Also Eicosapentaenoic Acid (EPA) (↓)		C11 Hydrocarbon (↓)
O-Phosphocolamine (↓)		Dehydroalanine Possibly From Cysteine (↓)
6-Hydroxynicotinic Acid (↓)