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. 2017 Sep 10;15(9):285. doi: 10.3390/md15090285

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© 2017 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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A biogenetic hypothesis for the adociasulfates. (A) A biosynthetic scheme summarizing the proposed biogenetic hypothesis for the origin of adociasulfates. (B) A hypothetical adociasulfate gene cluster was constructed based on the most probable biosynthetic origin, as addressed in this review. In this scenario, the pathway is assumed to be part of a bacterial genome. Black genes represent those directly involved in biosynthesis, white genes are those indirectly involved in biosynthesis, and those bordered with a dashed line have the potential to be entirely absent from the cluster.