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. 2017 Sep 20;15(9):294. doi: 10.3390/md15090294

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of MP-A on TNF-α and PGE2 production and iNOS and COX-2 protein expression in LPS-stimulated THP-1 cells. (A,B) MP-A inhibition of TNF-α and PGE2 production in LPS-stimulated THP-1 cells. TNF-α (6-h stimulation) and PGE2 (24-h stimulation) were measured via an ELISA. The data represent three independent experiments. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001 compared to the LPS group. (C,D) MP-A inhibition of iNOS and COX-2 protein expression, as assessed by western blotting analysis in LPS-stimulated THP-1 cells. * p < 0.05, ** p < 0.01, and *** p < 0.001, when compared to controls; ^# p < 0.05, ^## p < 0.05, and ^### p < 0.001 compared to the LPS group (n = 3).