Table 1.
Urinary tract stones
|
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---|---|---|---|---|---|
na | Yes Annual change (beta ± SE) | No Annual change (beta ± SE) | pa | pb | |
Total hip | 9717 | −0.0013 ± 0.0003 | −0.00113 ± 0.00006 | 0.57 | 0.33 |
Sensitivity 1c | 9446 | −0.0012 ± 0.0003 | −0.00114 ± 0.00006 | 0.91 | 0.49 |
Sensitivity 2d | 9717 | −0.0012 ± 0.0003 | −0.00114 ± 0.00006 | 0.90 | 0.48 |
Femoral neck | 9717 | −0.0007 ± 0.0003 | −0.00087 ± 0.00007 | 0.50 | 0.49 |
Sensitivity 1c | 9446 | −0.0009 ± 0.0003 | −0.00087 ± 0.00007 | 0.99 | 0.96 |
Sensitivity 2d | 9717 | −0.0009 ± 0.0003 | −0.00087 ± 0.00007 | 1.00 | 0.97 |
Lumbar spine | 9730 | 0.0046 ± 0.0004 | 0.00525 ± 0.00010 | 0.13 | 0.38 |
Sensitivity 1c | 9457 | 0.0042 ± 0.0005 | 0.00523 ± 0.00010 | 0.03 | 0.17 |
Sensitivity 2d | 9730 | 0.0042 ± 0.0005 | 0.00525 ± 0.00010 | 0.02 | 0.16 |
Whole body | 9718 | 0.0030 ± 0.0003 | 0.00251 ± 0.00008 | 0.15 | 0.38 |
Sensitivity 1c | 9447 | 0.0029 ± 0.0004 | 0.00250 ± 0.00008 | 0.32 | 0.75 |
Sensitivity 2d | 9718 | 0.0029 ± 0.0004 | 0.00250 ± 0.00007 | 0.32 | 0.75 |
Coefficient of year (g/cm2 per year) in linear mixed model for BMD stratified on time-dependent urinary tract stone status. Linear mixed model was used to estimate beta coefficients and significance level.
Unadjusted; p value is test across slopes for those with kidney stones compared to those without.
Adjusted for age, race, BMI, physical functioning, age at menopause, education, income, region, smoking, fracture at age 55+ years, parent with fracture after 40 years old, general health, alcohol intake, diabetes history, hormone therapy use, physical activity, bisphosphonate, calcitonin, oral corticosteroids, antiepileptic, proton pump inhibitor, thiazide, loop diuretic, thyroid meds, HT arm, DM arm, CaD arm, and diet and supplement intake.
Sensitivity analysis 1: Including only women with baseline urinary tract stones (prevalent urinary tract stones) or never urinary tract stones (not incident).
Sensitivity analysis 2: Including the portion of longitudinal data for which urinary tract stones status did not change; this includes all the women in sensitivity analysis 1 and the initial data for women who developed urinary tract stones during study.