Figure 5.
Effect of polydeoxyribonucleotide (PDRN) treatment on the adenosine A2A receptor, tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) expressions. Actin was used as an internal control (46 kDa). Upper: The results of ban detection using the enhanced chemiluminescence (ECL) detection kit. (A) Control and 24 h after sacrifice group; (B) Lung injury and 24 h after sacrifice group; (C) Lung injury with PDRN-treatment and 24 h after sacrifice group; (D) Control and 72 h after sacrifice group; (E) Lung injury and 72 h after sacrifice group; and (F) Lung injury with PDRN-treatment and 72 h after sacrifice group. Lower: The relative expressions of adenosine A2A receptor (left), TNF-α (middle), and IL-6 (right) in each group. * represents p < 0.05 compared to the control and 24 h after sacrifice group. # represents p < 0.05 compared to the lung injury and 24 h after sacrifice group.