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. 2017 Aug 29;18(9):1869. doi: 10.3390/ijms18091869

Figure 1.

Figure 1

NanoSIMS secondary ion maps of 31P/12C2, 34S/12C2, 14N12C/12C2, 15N12C/14N12C, 102Ru/12C2, and 13C12C/12C2 and TEM images of MDA-MB-231 cells treated with 15N/13C-labelled RAPTA-T (500 μM, 24 h). Blue boxes indicate Ru-enriched hotspots, yellow boxes indicate 15N-enriched hotspots, and green boxes indicate hotspots co-enriched with 15N and Ru. Cellular organelles are labeled in the TEM image.