Figure 9.

Electrical activity of simulated ventricular-like and atrial-like hiPSC-CMs. (A,B) Action potential during 1 Hz stimulation of (A) a ventricular-like and (B) an atrial-like model cell in the absence and presence of an additional I_K1-like current, as applied by Meijer van Putten et al. [5], Bett et al. [14], or Rocchetti et al. [15], or a hyperpolarising current of constant amplitude, as applied by Jara-Avaca et al. [16]. Insets: maximum AP upstroke velocity. (C,D) Associated additional current.