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. 2017 Aug 30;18(9):1873. doi: 10.3390/ijms18091873

Table 4.

Action potential parameters of hiPSC-CM model cell upon injection of synthetic IK1.

Action Potential Parameter Meijer van Putten et al. IK1 Rocchetti et al. IK1 Bett et al. IK1
Vent Atr Vent Atr Vent Atr
MDP (mV) −83.9 −84.0 −79.5 −79.4 −82.2 −82.8
Vmax (V/s) 129.1 209.6 87.0 149.8 130.4 210.0
APA (mV) 134.8 138.2 120.3 129.2 132.1 136.2
AP plateau (mV) 112.4 110.8 107.0 106.0 101.7 100.4
APD20 (ms) 30.8 20.8 42.4 31.5 14.8 8.7
APD50 (ms) 240.9 135.1 248.5 138.3 94.8 65.8
APD90 (ms) 306.6 183.3 311.5 189.6 144.4 96.5

Data obtained with ventricular-like and atrial-like hiPSC-CM model cells of Paci et al. [30,31]. Vent: ventricular-like cell; Atr: atrial-like cell; MDP: maximum diastolic potential; Vmax: maximum upstroke velocity; APA: action potential amplitude; AP plateau: AP plateau amplitude; APD20, APD50, and APD90: action potential duration at 20%, 50%, and 90% repolarisation, respectively.