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Efficacy of S. typhimurium A1-R, 5-fluorouracil (5-FU) and cisplatinum (CDDP) on a melanoma PDOX model. (A) Experimental scheme; (b1) mean change in tumor volume plotted against time, as shown in untreated and control tumors; (b2) linear prediction versus time curves for untreated control and treated tumors; (C) body weight comparison in nude mice after S. typhimurium A1-R and/or 5-FU and CDDP therapy [34]. ** p < 0.01, compared with the untreated control group.
