Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Aug 31;18(9):1875. doi: 10.3390/ijms18091875

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2017 by the author.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Time-coursed treatment efficacy on the BRAF-V600E mutant melanoma PDOX. Line graph shows tumor volume at each point relative to the initial tumor volume. All treatments significantly inhibited tumor growth compared to the untreated control (TEM: p = 0.0081, recombinant methioninase (rMETase): p = 0.0037, TEM/rMETase: p = 0.0024). In addition, TEM and rMETase combination therapy was significantly stronger than both TEM (p = 0.0051) and rMETase (p = 0.0051) alone at day 14. There was no significant difference between TEM and rMETase. ** p < 0.01. Error bars = SD [77].