Table 10.

Bone regeneration/bone injury healing effects of β-glucans—human study.

β-Glucan	Organism	Analysis	Results	Reference
Polycalcium (Polycan + calcium lactate-gluconate)	40–60 years old healthy women	Anti-osteoporotic effect, Measurement of changes in DPYR, OSC, BALP, CTx, and P levels	Improved bone metabolism and well tolerated polycalcium effect.	[185]
Polycan	40–70 years old, healthy premenopausal women	Anti-osteoporotic effect, Measurement of changes in OCS, BALP, Ca, and P levels	Increased changes in OSC, and BALP, Ca, P, CTx, NTx, and DPYR. Increase in CTx was modestly inhibited.	[186]

DPYR: Deoxypyridinoline; OSC: Osteocalcium; BALP: Bone-specific alkaline phosphatase; Ca: Calcium; P: Phosphorus; CTx: C-telopeptide of collagen cross-links; NTx: N-telopeptide of collagen cross-link.