Table 1.
List of up- and downregulated microRNAs (miRNAs) in intestinal biopsies of patients affected by coeliac disease (CD) (active CD, on gluten free-diet, with or without anemia) as compared to control subjects. The list of miRNAs have been obtained by the papers indicated in the last column.
| Upregulated miRNAs | Downregulated miRNAs | Reference |
|---|---|---|
| Upregulated miRNAs in biopsies of CD patients (active and on gluten free-diet) | Downregulated miRNAs in biopsies of CD patients (active and on gluten free-diet) | [14] |
| miR-182, miR-196a, miR-330, miR-449a, miR-492, miR-500, miR-503, miR-504, miR-644 | miR-105, miR-124a, miR-135a, miR-189, miR-202, miR-219, miR-299-5p, miR-323, miR-379, miR-380-5p, miR-409-5p, miR-412, miR-512-3p, miR-566, miR-576, miR-600, miR-614, miR-616, miR-618, miR-631, miR-659 | |
| Upregulated in GFD patients | Downregulated in GFD patients | [15] |
| miR-422a, miR-551a, miR-1285-3p, miR-3681-5p | N.A. | |
| Upregulated in CD patients | Downregulated in CD patients | |
| miR-24-2-5p, miR-2113, miR-4300, miR-551b-5p, miR-519d, miR-642b-3p, miR-523-3p, miR-491-3p | miR-215, miR-451a, miR-192-5p, miR-31-5p, miR-194-5p, miR-338-3p | |
| Upregulated in CD patients with anaemia | Downregulated in CD patients with anaemia | |
| miR-491-3p, miR-337-3p, miR-2355-3p, miR-3148, miR-24-2-5p , miR-920, miR-638, miR-146b-3p, miR-1304-5p, miR-498, miR-490-3p, miR-1285-3p, miR-3183, miR-1290, miR-1299, miR-1270, miR-3663-5p, miR-618, miR-3135a, miR-4268, miR-4300, miR-4324, miR-300, miR-519d, miR-422a, miR-302a-3p, miR-3654, miR-3611, miR-4329, miR-3681-5p, miR-551b-5p, miR-4303, miR-642a-5p/miR-642b-5p, miR-550b-3p, miR-593-3p, miR-146a-5p, miR-1273e, miR-432-5p | miR-215, miR-31-5p, miR-193a-5p, miR-194-5p, miR-192-5p, miR-451a, miR-192-3p, miR-138-1-3p, miR-30b-5p, miR-664-5p | |
| Upregulated miRNAs in human biopsies of CD patients | Downregulated miRNAs in human biopsies of CD patients | [16] |
| N.A. | miR-192-5p, miR-194-5p, miR-197, miR-31-5p, miR-338-3p | |
| Upregulated miRNAs in human biopsies of CD patients | Downregulated miRNAs in human biopsies of CD patients | [17] |
| miR-21-5p, miR-21-3p, miR-486-5p | miR-192-5p, miR-31-5p, miR-338-3p |