Table 2.
Markers of oxidative stress.
C | CKD | CKDA | CKDL | |
---|---|---|---|---|
Oxidized proteins in the cortex (DNPH nmol/mg protein) | 0.90 ± 0.30 | 122.2 ± 20.99 * | 59.87 ± 4.06 *,+ | 76.7 ± 6.29 *,+ |
Oxidized proteins in the medulla (DNPH nmol/mg protein) | 1.09 ± 0.30 | 74.42 ± 1.82 * | 36.27 ± 5.19 *,+ | 63.04 ± 3.46 *,+ |
Lipid peroxidation in the cortex (4HNE nmol/mg protein) | 1.27 ± 0.28 | 6.18 ± 0.32 * | 2.26 ± 0.4 + | 2.04 ± 0.88 + |
Lipid peroxidation in the medulla (4HNE nmol/mg protein) | 1.06 ± 0.36 | 6.13 ± 1.12 * | 1.88 ± 0.28 + | 0.92 ± 0.21 + |
C: control; CKD: chronic kidney disease; CKDA: chronic kidney disease, allicin-treated; CKDL: chronic kidney disease, losartan-treated. Data represent the mean ± SEM, n = 6. * p < 0.05 versus control; + p < 0.05 versus CKD; # p < 0.05 versus CKDA.