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Amiodarone and dronedarone induce dose‐dependent increases in KIR2.1 expression in COS‐7 cells. (A and B) Western blot analysis of KIR2.1 expression in COS‐7 cells treated with 2, 5, 10 or 20 μM amiodarone or 2, 5 or 10 μM dronedarone for 24 hrs. C indicates control (untreated) cells. Ponceau staining is used as loading control. Averaged data from three independent experiments are depicted in bar graphs in the lower part of both panels. *P < 0.05; **P < 0.01; ***P < 0.001.
