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. 2017 Apr 19;21(10):2514–2523. doi: 10.1111/jcmm.13172

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© 2017 The Authors. Journal of Cellular and Molecular Medicine published by John Wiley & Sons Ltd and Foundation for Cellular and Molecular Medicine.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A) Costaining of K_IR2.1‐GFP and LAMP1 in control (untreated) and cells treated with 10 μM amiodarone (A10) or 5 μM dronedarone (D5). Merged pictures are presented in colour. Individual staining patterns of the boxed parts are given in the lower six panels in b/w. Red arrows indicate regions of colocalization. Pearson coefficient of colocalization is presented as bars on the right. (B) Costaining of K_IR2.1‐GFP (green) and EEA1 (red) in control (untreated) and cells treated with 10 μM amiodarone (A10). Individual staining patterns of the boxed parts are given in the right panels in b/w. Pearson coefficient of colocalization is presented as bars on the right. (C) Costaining of K_IR2.1 (red) and Rab7‐GFP (green) in control (untreated) and cells treated with 10 μM amiodarone (A10) or 5 μM dronedarone (D5). Individual staining patterns of the boxed parts are given in the lower six panels in b/w. Pearson coefficient of colocalization is presented as bars on the right. Scale bars represent 5 μm. *P < 0.05.