Figure 3.
Effects of JK‐1 on ASP‐induced gastric mucosal injury. The mice were fasted for 36 hrs with free access to drinking water and then were treated as DRUG TREATMENTS AND EXPERIMENTAL DESIGN. (A‐D) The representative images of open stomach samples from the following groups: (A) control group, (B) ASP group, (C) ASP+JK‐1 group, (D) JK‐1 group. (E) Gastric ulcer area of the four groups was calculated with ImageJ software. (F) Mice were administered intragastrically with increasing doses of ASP. The gastric mucosa was collected and split for the measurement of relative H2S generation. Data were expressed as mean ± S.D. n = 4–6. *P < 0.05, **P < 0.01 versus control group, ##P < 0.01 versus ASP alone group.