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. 2017 Sep 27;17:661. doi: 10.1186/s12885-017-3649-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Western blot and qRT-PCR demonstrate that clusterin exert its influence in transdifferentiation between lung adenocarcinoma and lung squamous cell carcinoma. sCLU was added in concentration gradient, then, Western blot (a) and qRT-PCR (b & c) was performed as described in the Methods and the clusterin addition could increase SP-C protein expression in 2.75-fold, and decrease p63 protein expression in 0.65-fold (1.54 to 1). And also could increase SP-C mRNA expression in 4.05-fold, decreased p63 mRNA expression in 0.51-fold