Table 1.
Articles divided by tests, author, population, mean age, diagnosis and main results.
| Tests | Authors | Population (n) | Age Mean (SD) | Diagnosis (n) | Results |
|---|---|---|---|---|---|
| CogState | Lim et al., 2013 | HC: 105aMCI: 48AD: 42 | HC: 73.62 (6.86)aMCI: 78.87 (6.92)AD: 79.57 (6.61) | HC aMCI AD |
High test-retest reliability and stability in all groups and adequate to detect AD-related cognitive impairment |
| Darby et al., 2012 | 263 older adults | 64.6 (7) | HC | Repetitive assessment indicating a population with risk of decline | |
| Hammers et al., 2012 | HC: 22MCI: 16AD: 37DLB: 5FTD: 7 | 70.5( 8.7) | HC, MCI, AD, DLB, FTD | Sensitivity, but not specificity, for diagnosing dementia | |
| Hammers et al., 2011 | HC: 23 MCI: 20AD: 52DLB: 10FTD: 9 | HC: 68.4 (9.5)MCI: 73.5 (5.9)AD: 70.8 (8.7)DLB: 70.4 (8.5)FTD: 64.2 (8.1) | HC, MCI, AD, DLB, FTD | Sensitive for cognitive impairment in established dementia and minimal practice effects at short test-retest intervals | |
| CNS Vital Signs | Gualtieri and Johnson, 2006 | 1069 | 7-90 | HC, neuropsychiatric patients, MCI and dementia | Psychometric characteristics and reliability similar to conventional tests, sensitive for cognitive impairment. Should be used as a screening instrument and not as substitute for formal neuropsychological testing |
| COGDRAS | Wesnes et al, 2010 | 51 | 76.5 (6.85) | Mild and moderate AD with acetylcholinesterase inhibitors | Good psychometric properties. Measures of psychomotor speed showed possible sensitivity for detecting decline over 6 months |
| Lepeleire, et al., 2005 | 152 | 80.01(7.13) | HC | Low sensitivity and specificity of subtests added to PBW battery in diagnosing dementia | |
| Mindstreams (Neurotrax) | Dwlatzky et al., 2010 | 170 | ≥60 | No impairment (7), questionable impairment (76), very mild (58), mild (26), moderate impairment (2), | Performance differed significantly across groups (p<0.001) poorer overall battery performance for those with greater impairment |
| Doninger et al., 2009 | 27 MCI22HC | MCI: 69.2(6.5)HC: 67.6(4.6) | MCI and HC | MCI performed poorly compared to HC participants in all domains, with significant differences in memory (p= .003; d= 0.96) executive function (p =.046; d=0.64), and overall battery performance (p=.041; d=0.63). | |
| Fillit et al., 2008 | 2.888 | 64.7(18.2) | Neurology (2.539); Primary care (286); Geriatrics (63) | 83% rated the test easy to use (p<0.001),. | |
| Doniger et al.,2006 | GDS: 72CSDD: 88 | GDS: 74.9 (6.9)CSDD: 78.4 (8.8) | HC, MCI, mild AD | Discriminated among MCI, mild AD, and HC participants following covariation for depression scale score in both cohorts, demonstrates that the battery is unaffected by depression | |
| Doniger et al.,2005 | 161 | 69.1 (9.3) | HC, MCI, mild dementia | Discriminating between demented and non-demented individuals=AUC=0.886 (p<0.001). For discriminating between cognitively healthy individuals and non-cognitively healthy individuals AUC=0.823 (p<0.001) |
SD: Standard Deviation; MCI: mild cognitive impairment; aMCI: amnestic mild cognitive impairment; AD: Alzheimer´s disease; FTD: frontotemporal dementia; DLB: dementia with Lewy bodies; HC: healthy control; GDS: Global Depression Scale; CSDD: Cornell Scale for Depression in Dementia.