Table 1.
Degree of severity | |||||
---|---|---|---|---|---|
Little or no burden (n=26) n (%) |
Mild to moderate burden (n=23) n (%) |
Moderate to severe burden (n=24) n (%) |
Severe burden (n=19) n (%) |
||
Age of patient, years§ | 75 (57-88) | 76 (60-92) | 76 (40-89) | 73 (56-84) | |
Time since diagnosis, years§ | 1 (0-3) | 2 (1-3)* | 2 (1-3)* | 2 (0-3)* | |
Dementia sub-type | Alzheimer’s dementiaz | 18 (69.2%) | 16 (69.6%) | 21 (87.5%) | 13 (68.4%) |
Vascular dementia | 4 (15.4%) | 4 (17.4%) | 2 (8.3%) | 3 (15.8%) | |
Frontotemporal dementia | 1 (3.9%) | 1 (4.4%) | 1 (4.2%) | 3 (15.8%) | |
Mixed dementia | 3 (11.5%) | 2 (8.7%) | 0 (0.0%) | 0 (0.0%) | |
Treatment, type | None | 2 (7.7%) | 4 (17.4%) | 5 (20.8%) | 3 (15.8%) |
Cholinesterase inhibitors | 19 (73.1%) | 8 (34.8%) | 6 (25.0%) | 6 (31.6%) | |
Memantine | 2 (7.7%) | 4 (17.8%) | 1 (4.8%) | 2 (10.5%) | |
Cholinesterase inhibitors plus memantine | 3 (11.5%) | 7 (30.4%) | 12 (50.0%) | 8 (42.1%) | |
Global Dementia Scale, points§ | 4 (3-6) | 5 (3-5)* | 5 (3-6)* | 5 (3-6)* |
Data are expressed as median (minimum and maximum values);
p-value for the comparison with the little or no burden group;
** p-value for the comparison with the mild to moderate burden group; *** p-value for the comparison with the moderate to severe burden group.