Table 2.
CBS: Pathologic correlations.
| Study Pathology |
Boeve, 200337 | Hodges, 200458 |
Josephs, 200659 |
McMonagle, 200629 |
Shelley, 20096 | Ling, 201034 |
Lee, 20117 |
Total, n (%) |
|---|---|---|---|---|---|---|---|---|
| CBS cases, n | 34 | 9 | 21 | 19 | 12 | 21 | 40 | 156 (100) |
| CBD | 18 | 7 | 10 | 11 | 6 | 5 | 14 | 71 (45.5) |
| PSP | 6 | 0 | 10 | 1 | 0 | 6 | 5 | 28 (18.0) |
| AD | 3 | 0 | 0 | 1 | 6 | 5 | 9 | 24 (15.4) |
| Pick’s disease | 2 | 0 | 1 | 3 | 0 | 0 | 1 | 7 (4.5) |
| DLDH | 2 | 1 | 0 | 0 | 0 | 1 | 0 | 4 (2.6) |
| PD | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 (1.3) |
| FTLD-TDP43 | 0 | 1 | 0 | 2 | 0 | 1 | 5 | 9 (5.8) |
| FTLD-TDP43 + MND | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 (0.6) |
| CJD | 3 | 0 | 0 | 1 | 0 | 0 | 0 | 4 (2.6) |
| MST | 0 | 0 | 0 | 0 | 0 | 1 | 1 (0.6) | |
| Mixed diseasea | 0 | 0 | 0 | 0 | 0 | 0 | 5 | 5 (3.2) |
a
Mixed cases: 2 PSP, 1 CBD, 1 FTLD-TDP, all mixed with intermediate probability of Alzheimer’s disease. CBD: Corticobasal degeneration; PSP: Progressive supranuclear palsy; AD: Alzheimer’s disease; DLDH: Dementia lacking specific histology; PD: Parkinson’s disease; FTLD-TDP43: Frontotemporal lobar degeneration with TDP-43 inclusions; MND: Motor neuron disease; CJD: Creutzfeldt- Jacob disease; MST: Multiple system tauopathy without argyrophilia.