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. 2016 Oct-Dec;10(4):320–326. doi: 10.1590/s1980-5764-2016dn1004011

Table 2.

Clinical, cognitive and total magnetic resonance imaging in patients with specific topographic MRI changes.

  Hyperintense T2
signal Globus
Pallidus (7)
Without Hyperintense
T2 signal
Mesencephalon
Globus Pallidus (13)
p Hyperintense
T2 signal
Mesencephalon
(8)
Without
Hyperintense
T2 signal
Mesencephalon (12)
p
Age 28.29±6.02 31.0±7.90 0.438 27.5±7.17 31.75±7.09 0.181
Motor Symptoms Scale 4.14±1.21 2.0±1.75 0.013 4.38±1.40 1.64±1.2 0.001
Education (Years) 9.71±3.54 11.92±3.73 0.311 9.25±5.06 12.42±1.83 0.02
Duration of disease (years) 10.14±6.14 12.62±8.66 0.699 9.5±6.27 13.25±8.59 0.427
MMSE 25.57±2.50 27.31±2.28 0.115 25.13±2.64 27.75±1.71 0.025
Animal fluency 13.14±4.74 19.62±5.50 0.019 12.38±4.43 20.67±3.86 0.001
FAS 15.43±10.76 26.15±11.91 0.037 14.25±9.09 27.83±11.51 0.012
M2 8.57±0.53 9.46±0.51 0.011 8.75±0.70 9.42±0.51 0.057
M5 7.86±1.46 8.85±1.28 0.251 7.75±1.16 9±1.34 0.082
FAB 12.14±1.95 13.38±3,22 0.211 11.75±2.76 13.75±2.73 0.098
Stroop 3 5.14±4.37 4.08±5.18 0.438 6.88±6.12 2.83±3.04 0.082
CERAD 14.0±1.91 14.31±1.37 0.938 13.63±2.264 14.58±0.66 0.678
DRS 126.14±12.21 135.85±8.58 0.012 124.5±12.75 137.75±4.53 0.012
Cubes (WAIS) 8.14±3.02 7.62±2.90 1.0 6.38±2.77 8.75±2.66 0.135
Hooper 62.43±10.58 60.38±6.13 0.877 64.13±9.56 59.08±5.86 0.208
WCST 2.29±0.95 2.23±1.58 0.699 2.13±1.35 2.33±1.43 0.910
Total MRI 9.86±1.95 6.54±2.84 0.019 9.88±2.10 6.25±2.63 0.010
Hyperintense T2 signal MRI 4.29±1.60 1.77±1.73 0.008 5.75±1.48 2.08±1.44 <0.001
Pfeffer scale 3.29±2.36 1.46±2.72 0.008 3.88±2.74 0.98±1.97 0.012

MMSE: Mini-Mental State Examination; M2: memory (learning); M5: memory (delayed recall); AF: animal fluency; FAS: phonemic fluency; FAB: Frontal Assessment Battery; DRS: Dementia Rating Scale; WCST: Wisconsin Card Sorting Test.