Table 2.
Clinical, cognitive and total magnetic resonance imaging in patients with specific topographic MRI changes.
Hyperintense T2 signal Globus Pallidus (7) |
Without Hyperintense T2 signal Mesencephalon Globus Pallidus (13) |
p | Hyperintense T2 signal Mesencephalon (8) |
Without Hyperintense T2 signal Mesencephalon (12) |
p | |
---|---|---|---|---|---|---|
Age | 28.29±6.02 | 31.0±7.90 | 0.438 | 27.5±7.17 | 31.75±7.09 | 0.181 |
Motor Symptoms Scale | 4.14±1.21 | 2.0±1.75 | 0.013 | 4.38±1.40 | 1.64±1.2 | 0.001 |
Education (Years) | 9.71±3.54 | 11.92±3.73 | 0.311 | 9.25±5.06 | 12.42±1.83 | 0.02 |
Duration of disease (years) | 10.14±6.14 | 12.62±8.66 | 0.699 | 9.5±6.27 | 13.25±8.59 | 0.427 |
MMSE | 25.57±2.50 | 27.31±2.28 | 0.115 | 25.13±2.64 | 27.75±1.71 | 0.025 |
Animal fluency | 13.14±4.74 | 19.62±5.50 | 0.019 | 12.38±4.43 | 20.67±3.86 | 0.001 |
FAS | 15.43±10.76 | 26.15±11.91 | 0.037 | 14.25±9.09 | 27.83±11.51 | 0.012 |
M2 | 8.57±0.53 | 9.46±0.51 | 0.011 | 8.75±0.70 | 9.42±0.51 | 0.057 |
M5 | 7.86±1.46 | 8.85±1.28 | 0.251 | 7.75±1.16 | 9±1.34 | 0.082 |
FAB | 12.14±1.95 | 13.38±3,22 | 0.211 | 11.75±2.76 | 13.75±2.73 | 0.098 |
Stroop 3 | 5.14±4.37 | 4.08±5.18 | 0.438 | 6.88±6.12 | 2.83±3.04 | 0.082 |
CERAD | 14.0±1.91 | 14.31±1.37 | 0.938 | 13.63±2.264 | 14.58±0.66 | 0.678 |
DRS | 126.14±12.21 | 135.85±8.58 | 0.012 | 124.5±12.75 | 137.75±4.53 | 0.012 |
Cubes (WAIS) | 8.14±3.02 | 7.62±2.90 | 1.0 | 6.38±2.77 | 8.75±2.66 | 0.135 |
Hooper | 62.43±10.58 | 60.38±6.13 | 0.877 | 64.13±9.56 | 59.08±5.86 | 0.208 |
WCST | 2.29±0.95 | 2.23±1.58 | 0.699 | 2.13±1.35 | 2.33±1.43 | 0.910 |
Total MRI | 9.86±1.95 | 6.54±2.84 | 0.019 | 9.88±2.10 | 6.25±2.63 | 0.010 |
Hyperintense T2 signal MRI | 4.29±1.60 | 1.77±1.73 | 0.008 | 5.75±1.48 | 2.08±1.44 | <0.001 |
Pfeffer scale | 3.29±2.36 | 1.46±2.72 | 0.008 | 3.88±2.74 | 0.98±1.97 | 0.012 |
MMSE: Mini-Mental State Examination; M2: memory (learning); M5: memory (delayed recall); AF: animal fluency; FAS: phonemic fluency; FAB: Frontal Assessment Battery; DRS: Dementia Rating Scale; WCST: Wisconsin Card Sorting Test.