Table 2.

Summary of key findings of the study.

A – [18F]FDG-PET analysis using SVC of the PCC with SPM8*
Comparisons	Cluster size (mm3)	pFWE	p#	Z score
AD × CG
Right posterior cingulate gyrus	129	< 0.001	< 0.00001	7.49
Left posterior cingulate gyrus	241	< 0.001	< 0.00001	7.56
MCI × CG	No suprathreshold clusters (p >0.001)
B – Naa/mI MRS ROI**
Comparisons				p
AD × CG				0.024
MCI × CG				0.060
C – Correlation analysis
			Correlation	p
[ 18 F] FDG-PET × Naa/mI			0.361	0.001
D – ROC curve analysis of the different PCC ROIs
			Area under the ROC curve
[ 18 F] FDG-PET			0.935
Naa/mI			0.708

^*Results at the peak voxel level (ANOVA and post-hoc unpaired t-test);

^**ANOVA and post-hoc unpaired t-test with SPSS;

^#p value uncorrected for multiple comparisons; pFWE: p value corrected for multiple comparisons with the familywise error method; MCI: Amnestic MCI; CG: Control group; SPM: statistical parametric mapping; SVC: small volume correction method, directed to the PCC.