Table 4.
PRNP polymorphisms in notified cases compared to controls.
| Residue Position |
Genotype | Exposed (%) | Crude | |||
|---|---|---|---|---|---|---|
| Controls n=202 (%) |
Possible CJD n=27 (%) |
OR (95% CI) |
p Value |
|||
| Octarepeat |
R12234 R12234/R1234 R1234 |
192 (95.0) 10 (5.0) 0 (0) |
25 (92.6) 2 (7.4) 0 (0) |
1.00 2.68 (0.68-10.59) NA |
||
| 117 | Ala/Ala Ala/Alasilent |
193 (95.5) 9 (4.5) |
25 (92.6) 2 (7.4) |
1.00 1.72 (0.35-8.40) |
||
| 129 | Met/Met Met/Val Val/Val |
112 (55.4) 81 (40.1) 9 (4.5) |
15 (55.6) 6 (22.2) 6 (22.2) |
1.00 0.56 (0.21-1.45) 4.98 (1.55-15.96) |
||