Table 5.
PRNP polymorphisms in probable sCJD cases compared to the controls.
| Residue Position |
Genotype | Exposed (%) | Crude | |||
|---|---|---|---|---|---|---|
| Controls n=202 (%) |
Probable sCJD n=15(%) |
OR (95% CI) |
p Valuea |
|||
| Octarepeat |
R12234 R12234/R1234 R1234 |
192 (95.0) 10 (5.0) 0 (0) |
14 (93.3) 1 (6.7) 0 (0) |
1.00 1.37 (0.16-11.49) NA |
||
| 117 | Ala/Ala Ala/Alasilent |
193 (95.5) 9 (4.5) |
14 (93.3) 1 (6.7) |
1.00 1.53 (0.18-12.95) |
||
| 129 | Met/Met Met/Val Val/Val |
112 (55.4) 81 (40.1) 9 (4.5) |
11 (73.3) 2 (13.3) 2 (13.3) |
1.00 0.25 (0.05-1.17) 2.26 (0.43-11.81) |
||