Table 6.
PRNP polymorphisms in probable sCJD cases compared to the other notified cases.
| Residue Position |
Genotype | Exposed (%) | Crude | |||
|---|---|---|---|---|---|---|
| Probable s CJD n=15 (%) |
Other notified n=12 (%) |
OR (95% CI) |
p Valuea |
|||
| Octarepeat |
R12234 R12234/R1234 R1234 |
14 (93.3) 1 (6.7) 0 (0) |
11 (91.7) 1 (8.3) 0 (0) |
1.00 1.27 (0.07-22-72) NA |
||
| 117 | Ala/Ala Ala/Alasilent |
14 (93.3) 1 (6.7) |
11 (91.7) 1 (8.3) |
1.00 1.27 (0.07-22.72) |
||
| 129 | Met/Met Met/Val Val/Val |
11 (73.3) 2 (13.3) 2 (13.3) |
5 (41.7) 4 (33.3) 3 (25.0) |
1.00 4.40 (060-32.50) 3.30 (0.41-26.37) |
||